A cikin 'yan shekarun nan, fasahar nano-magungunan ƙwayoyi babbar sabuwar fasaha ce a fasahar shirya magunguna. Nano kwayoyi kamar nanoparticles, ball ko nano capsule nanoparticles a matsayin tsarin dako, da kuma ingancin barbashi a wata hanya tare bayan magani, kuma za a iya sanya kai tsaye zuwa fasaha sarrafa nanoparticles.
Idan aka kwatanta da magungunan na al'ada, nano-magungunan suna da fa'idodi da yawa waɗanda ba za su iya kwatantawa da magungunan gargajiya ba:
Wani jinkirin sakin miyagun ƙwayoyi, canza rabin rayuwar miyagun ƙwayoyi a cikin jiki, tsawaita lokacin aikin miyagun ƙwayoyi;
Ana iya kaiwa ga takamaiman sashin da aka yi niyya bayan an sanya shi cikin magani mai shiryarwa;
Don rage sashi, rage ko kawar da sakamako mai guba a ƙarƙashin yanayin tabbatar da inganci;
Ana canza tsarin jigilar membran don ƙara haɓakar ƙwayar ƙwayar cuta zuwa biofilm, wanda ke da amfani ga ƙwayar ƙwayar cuta ta miyagun ƙwayoyi da kuma wasan kwaikwayon tasirin miyagun ƙwayoyi.
Don haka ga waɗancan buƙatun tare da taimakon mai ɗaukar kaya don isar da magunguna zuwa takamaiman maƙasudi, ba da wasa ga rawar jiyya dangane da nanodrugs, ƙirar mai ɗaukar hoto don haɓaka ingantaccen niyya na miyagun ƙwayoyi yana da mahimmanci.
Kwanan nan sanarwar ta ce jami'ar New South Wales, Australia, masu binciken sun samar da wata sabuwar hanya, za ta iya canza siffar nano magungunan da ke dauke da kwayar cutar, hakan zai taimaka wajen jigilar magungunan cutar daji da aka saki a cikin tumor, inganta tasirin maganin rigakafi. -magungunan daji.
Polymer kwayoyin a cikin bayani za a iya ta atomatik kafa vesicle m siffar siffar siffar siffar siffar siffar siffar siffar siffar siffar siffar siffar siffar siffar siffar siffar siffar siffar siffar siffar siffar siffar siffar siffar siffar siffar siffar siffar siffar siffar siffar polymer, yana da abũbuwan amfãni daga m kwanciyar hankali, aiki bambancin da ake amfani da ko'ina a matsayin magani m, amma, da bambanci, kamar kwayoyin cuta da kuma cutar a cikin yanayi ne tubes, sanduna. , kuma sifofin halittun da ba masu siffar zobe ba na iya samun sauƙin shiga jiki. Saboda vesicles na polymer suna da wahala su samar da wani tsari maras kyau, wannan yana iyakance ikon polymer ɗin don isar da magunguna zuwa inda yake a jikin ɗan adam zuwa wani ɗan lokaci.
Masu bincike na Ostiraliya sun yi amfani da microscope na cryoelectron don lura da canje-canjen tsarin kwayoyin polymer a cikin bayani. Sun gano cewa ta hanyar canza adadin ruwa a cikin ƙauyen, za a iya daidaita siffar da girman nau'in polymer vesicles ta hanyar canza yawan ruwa a cikin sauran ƙarfi.
Mawallafin marubuci kuma jami'ar New South Wales institute of chemistry of pine parr sol, ya ce: "Wannan ci gaban yana nufin za mu iya samar da siffar polymer vesicle na iya canzawa tare da yanayi, kamar oval ko tubular, da kuma kunshin magunguna a ciki." Shaidu na farko sun nuna cewa mafi na halitta, masu ɗaukar magungunan nano-kwayoyin da ba su da kyau suna iya shiga ƙwayoyin tumor.
An buga binciken a kan layi a cikin sabuwar fitowar mujallolin sadarwar yanayi.
Lokacin aikawa: Maris-16-2018