Bariumthiab nws cov compounds
Lub npe tshuaj nyob rau hauv Suav: Barium
Lub npe Askiv:Barium, Ba
Toxic mechanism: Bariumyog ib tug mos, silver dawb luster alkaline ntiaj teb hlau uas muaj nyob rau hauv cov xwm nyob rau hauv daim ntawv ntawm cov tshuaj lom barite (BaCO3) thiab barite (BaSO4). Barium tebchaw yog dav siv nyob rau hauv ceramics, iav kev lag luam, steel quenching, kev kho mob sib piv cov neeg sawv cev, tshuaj tua kab, tshuaj reagent ntau lawm, thiab lwm yam. Feem ntau barium tebchaw muaj xws li barium chloride, barium carbonate, barium acetate, barium nitrate, barium sulfate, barium sulfide,barium oxidebarium hydroxide, barium stearate, thiab lwm yam.Barium hlauyuav luag tsis muaj tshuaj lom, thiab cov tshuaj lom ntawm cov tshuaj barium muaj feem xyuam rau lawv cov solubility. Soluble barium tebchaw muaj tshuaj lom heev, thaum barium carbonate, txawm tias yuav luag insoluble hauv dej, yog tshuaj lom vim nws solubility hauv hydrochloric acid los tsim barium chloride. Lub ntsiab mechanism ntawm barium ion lom yog cov blockage ntawm calcium nyob rau hauv cov poov tshuaj nyob rau hauv lub hlwb los ntawm barium ions, uas ua rau kom ib tug nce nyob rau hauv lub cellular poov tshuaj thiab txo nyob rau hauv extracellular poov tshuaj concentration, uas ua rau hypokalemia; Lwm cov kws tshawb fawb ntseeg tias barium ions tuaj yeem ua rau arrhythmia thiab cov tsos mob ntawm plab hnyuv los ntawm ncaj qha stimulating myocardium thiab cov leeg nqaij. Kev nqus ntawm solublebariumCov tshuaj nyob rau hauv lub plab zom mov zoo ib yam li cov calcium, suav txog kwv yees li 8% ntawm tag nrho cov koob tshuaj. Cov pob txha thiab cov hniav yog qhov chaw tso nyiaj tseem ceeb, suav txog ntau dua 90% ntawm tag nrho lub cev load.Bariumnoj ntawm qhov ncauj yog tsuas yog tawm los ntawm cov quav; Feem ntau ntawm cov barium lim los ntawm ob lub raum yog reabsorbed los ntawm lub raum tubules, tsuas yog ib qho me me tshwm sim hauv cov zis. Kev tshem tawm ib nrab-lub neej ntawm barium yog li 3-4 hnub. Cov kab mob barium lom feem ntau tshwm sim los ntawm kev noj cov tshuaj barium xws li fermentation hmoov, ntsev, alkali hmoov, hmoov nplej, alum, thiab lwm yam. Kuj tseem muaj cov lus ceeb toom ntawm barium lom los ntawm cov dej haus uas muaj cov kab mob barium. Kev ua hauj lwm barium compound lom yog tsis tshua muaj thiab feem ntau absorbed los ntawm txoj hlab pa los yog puas daim tawv nqaij thiab mucous daim nyias nyias. Kuj tseem muaj cov lus ceeb toom ntawm kev lom neeg los ntawm kev raug barium stearate, feem ntau nrog subacute lossis mob ntev thiab lub sijhawm latent ntawm 1-10 lub hlis.
Kev kho mob ntim
Cov tshuaj lom neeg ntawm cov neeg noj barium chloride yog li 0.2-0.5g
Qhov koob tshuaj tuag rau cov neeg laus yog kwv yees li 0.8-1.0g
Cov tsos mob tshwm sim: 1. Lub sij hawm incubation ntawm qhov ncauj tshuaj lom yog feem ntau 0.5-2 teev, thiab cov neeg uas noj ntau heev tej zaum yuav muaj cov tsos mob lom nyob rau hauv 10 feeb.
(1) Cov tsos mob ntawm plab zom mov thaum ntxov yog cov tsos mob tseem ceeb: kub hnyiab ntawm qhov ncauj thiab caj pas, caj pas qhuav, kiv taub hau, mob taub hau, xeev siab, ntuav, mob plab, raws plab, ntuav, dej thiab cov quav tso zis, nrog rau hauv siab nruj, palpitations, thiab loog. hauv lub qhov ncauj, ntsej muag, thiab caj dab.
(2) Progressive leeg tuag tes tuag taw: Cov neeg mob pib tshwm sim nrog tsis tiav thiab flaccid limb tuag tes tuag taw, uas nce los ntawm cov leeg nqaij leeg mus rau caj dab, nqaij leeg, tus nplaig, cov leeg diaphragm, thiab cov leeg ua pa. Tus nplaig cov leeg tuag tes tuag taw tuaj yeem ua rau nqos tau nyuaj, muaj kev cuam tshuam ntawm kev sib txuas lus, thiab thaum muaj mob hnyav, cov leeg ua pa tuag tes tuag taw tuaj yeem ua rau ua pa nyuaj thiab ua rau tsis taus pa. (3) Kev puas tsuaj rau cov hlab plawv: Vim muaj cov tshuaj lom ntawm barium rau myocardium thiab nws cov teebmeem hypokalemic, cov neeg mob yuav ntsib kev puas tsuaj ntawm myocardial, arrhythmia, tachycardia, nquag lossis ntau yam mob ntxov ntxov, diphthongs, triplets, atrial fibrillation, conduction block, thiab lwm yam. Tej zaum yuav muaj mob arrhythmia, xws li ntau yam ectopic rhythms, thib ob lossis thib peb degree atrioventricular block, ventricular flutter, ventricular fibrillation, thiab txawm tias lub plawv nres. 2. Lub sij hawm incubation ntawm inhalation lom feem ntau fluctuates ntawm 0.5 mus rau 4 teev, manifested raws li cov tsos mob ntawm tus kab mob ua pa xws li mob caj pas, caj pas qhuav, hnoos, ua tsis taus pa luv, hauv siab nruj, thiab lwm yam., tab sis cov tsos mob ntawm digestive ib ntsuj av tau me ntsis, thiab. Lwm qhov kev kho mob tshwm sim zoo ib yam li qhov ncauj lom. 3. Cov tsos mob xws li loog, qaug zog, xeev siab, thiab ntuav tuaj yeem tshwm sim li ntawm 1 teev tom qab nqus cov tshuaj lom ntawm daim tawv nqaij los ntawm cov tawv nqaij puas thiab kub hnyiab. Cov neeg mob uas muaj qhov kub hnyiab tuaj yeem tshwm sim sai sai hauv 3-6 teev, suav nrog convulsions, ua pa nyuaj, thiab muaj kev puas tsuaj rau myocardial. Cov kev kho mob tshwm sim kuj zoo ib yam li qhov ncauj lom, nrog rau cov tsos mob me me. Tus mob feem ntau deteriorates sai heev, thiab siab ceev yuav tsum tau them rau thaum ntxov theem.
Kev kuaj mob
Cov txheej txheem yog raws li keeb kwm ntawm kev cuam tshuam rau barium tebchaw nyob rau hauv txoj kev ua pa, digestive ib ntsuj av, thiab daim tawv nqaij mucosa. Cov tsos mob tshwm sim xws li cov leeg tsis muaj zog tuag tes tuag taw thiab myocardial puas tsuaj tuaj yeem tshwm sim, thiab cov kev kuaj sim yuav qhia tau tias refractory hypokalemia, uas tuaj yeem kuaj tau. Hypokalemia yog lub hauv paus pathological ntawm mob hnyav barium lom. Kev poob qis ntawm cov leeg nqaij yuav tsum tau sib txawv ntawm cov kab mob xws li hypokalemic periodic tuag tes tuag taw, botulinum toxin lom, myasthenia gravis, nce muscular dystrophy, peripheral neuropathy, thiab mob polyradiculitis; Cov tsos mob ntawm plab hnyuv xws li xeev siab, ntuav, thiab mob plab yuav tsum paub qhov txawv ntawm cov zaub mov lom; Hypokalemia yuav tsum sib txawv ntawm cov kab mob xws li trialkyltin lom, metabolic alkalosis, familial periodic paralysis, thiab thawj aldosteronism; Arrhythmia yuav tsum sib txawv ntawm cov kab mob xws li cov kab mob digitalis lom thiab cov kab mob hauv lub plawv.
Txoj cai ntawm kev kho mob:
1. Rau cov neeg uas nkag mus rau hauv daim tawv nqaij thiab cov mucous daim nyias nyias kom tshem tawm cov tshuaj lom, qhov chaw tiv tauj yuav tsum tau muab ntxuav kom huv nrog dej huv tam sim ntawd kom tsis txhob nqus cov barium ions ntxiv. Cov neeg mob kub hnyiab yuav tsum tau kho nrog tshuaj tua kab mob thiab muab 2% mus rau 5% sodium sulfate rau hauv zos yaug qhov txhab; Cov neeg uas nqus tau los ntawm txoj kev ua pa yuav tsum tam sim ntawd tawm ntawm qhov chaw muaj tshuaj lom, yaug lawv lub qhov ncauj ntau zaus los ntxuav lawv lub qhov ncauj, thiab noj cov tshuaj sodium sulfate hauv qhov ncauj; Rau cov neeg uas noj los ntawm txoj hnyuv, lawv yuav tsum xub ntxuav lawv lub plab nrog 2% mus rau 5% sodium sulfate tov los yog dej, thiab ces muab 20-30 g ntawm sodium sulfate rau raws plab. 2. Cov tshuaj detoxification sulfate tuaj yeem tsim cov barium sulfate insoluble nrog barium ions kom detoxify. Thawj qhov kev xaiv yog txhaj 10-20ml ntawm 10% sodium sulfate intravenously, los yog 500ml ntawm 5% sodium sulfate intravenously. Nyob ntawm qhov xwm txheej, nws tuaj yeem rov siv dua. Yog tias tsis muaj sodium sulfate cia, sodium thiosulfate tuaj yeem siv tau. Tom qab tsim cov barium sulfate insoluble, nws raug tso tawm los ntawm ob lub raum thiab yuav tsum tau hloov cov kua dej thiab diuresis los tiv thaiv ob lub raum. 3. Kev kho kom raws sij hawm ntawm hypokalemia yog tus yuam sij rau kev kho mob plawv arrhythmia hnyav thiab ua pa ntawm cov leeg tuag tes tuag taw los ntawm barium lom. Lub hauv paus ntsiab lus ntawm potassium supplementation yog muab cov poov tshuaj txaus kom txog thaum lub electrocardiogram rov zoo li qub. Cov tshuaj lom me me feem ntau tuaj yeem ua rau qhov ncauj, nrog 30-60ml ntawm 10% potassium chloride muaj nyob rau txhua hnub hauv kev faib tshuaj; Cov neeg mob nruab nrab rau mob hnyav yuav tsum tau txhaj tshuaj potassium ntxiv. Cov neeg mob uas muaj cov tshuaj lom no feem ntau muaj kev kam rau siab dua rau cov poov tshuaj, thiab 10 ~ 20ml ntawm 10% potassium chloride tuaj yeem muab tso rau hauv cov hlab ntsha nrog 500ml ntawm lub cev saline lossis qabzib. Cov neeg mob hnyav tuaj yeem nce qhov concentration ntawm potassium chloride intravenous infusion mus rau 0.5% ~ 1.0%, thiab cov poov tshuaj ntxiv tuaj yeem ncav cuag 1.0 ~ 1.5g ib teev. Cov neeg mob tseem ceeb feem ntau xav tau cov koob tshuaj tsis zoo thiab kev noj cov tshuaj potassium sai sai hauv kev saib xyuas electrocardiographic. Kev nruj electrocardiogram thiab kev saib xyuas cov ntshav potassium yuav tsum tau ua thaum ntxiv cov poov tshuaj, thiab kev saib xyuas yuav tsum tau them rau kev tso zis thiab lub raum ua haujlwm. 4. Txhawm rau tswj arrhythmia, cov tshuaj xws li cardiolipin, bradycardia, verapamil, lossis lidocaine tuaj yeem siv rau kev kho mob raws li hom arrhythmia. Rau cov neeg mob uas tsis paub txog keeb kwm kho mob thiab tsis tshua muaj poov tshuaj electrocardiogram hloov pauv, cov ntshav potassium yuav tsum tau kuaj tam sim. Tsuas yog ntxiv cov poov tshuaj feem ntau ua tsis tau zoo thaum tsis muaj magnesium, thiab kev saib xyuas yuav tsum tau them nyiaj ntxiv rau magnesium nyob rau tib lub sijhawm. 5. Mechanical ventilation ua pa ua pa nqaij tuag tes tuag taw yog lub ntsiab ua rau tuag nyob rau hauv barium lom. Thaum cov leeg ua pa tsis ua pa tshwm, endotracheal intubation thiab tshuab ua pa yuav tsum tau ua tam sim ntawd, thiab tracheotomy yuav tsim nyog. 6. Kev tshawb fawb qhia tias kev ntsuas ntshav huv xws li hemodialysis tuaj yeem ua kom tshem tawm cov barium ions los ntawm cov ntshav thiab muaj qee yam kev kho mob. 7. Lwm yam kev pab txhawb nqa kev kho mob rau cov ntuav ntuav thiab raws plab heev yuav tsum tau muab cov kua dej tam sim kom tswj tau cov dej thiab electrolyte sib npaug thiab tiv thaiv kev kis kab mob thib ob.
Post lub sij hawm: Sep-12-2024