Pregabalin 99% CAS 148553-50-8
Taw qhia:
| Lub npe tshuaj: | Pregabalin |
| Synonyms: | 3- (Aminomethyl)-5-methyl-hexanoic acid |
| Cas No.: | 148553-50-8 |
| Molecular Formula: | C8H17NO2 |
| Molecular Luj: | 159.23 Nws |
| Molecular Structure: |
-Main Quality Performance index:
[Property]]: dawb crystal zoo li khoom.
[Cov ntsiab lus]]: ≥99.0%
[Kev sib hloov tshwj xeeb]]: [α]D20 + 9.5 ~ + 11.5o(C = 1,H2O)
-Siv:
Siv ua anticonvulsion, anti-epileptic tshuaj.
-Kev piav qhia
Pregabalin, ua lag luam raws li lub npe Lyrica ntawm lwm tus, yog cov tshuaj siv los kho mob vwm, mob neuropathic, fibromyalgia, thiab kev ntxhov siab dav dav. Nws siv rau kev qaug dab peg yog raws li kev kho mob ntxiv rau kev qaug dab peg ib nrab nrog lossis tsis muaj kev sib kis hauv cov neeg laus. Qee qhov kev siv cov tshuaj pregabalin intermediates muaj xws li mob ceg ceg, tiv thaiv migraines, kev ntxhov siab vim, thiab kev haus cawv. Thaum siv ua ntej kev phais nws tsis tshwm sim rau qhov mob tom qab phais tab sis yuav txo tau kev siv tshuaj opioids.
Cov kev mob tshwm sim feem ntau muaj xws li: pw tsaug zog, tsis meej pem, teeb meem nrog kev nco, kev ua haujlwm tsis zoo ntawm lub cev muaj zog, qhov ncauj qhuav, teeb meem tsis pom kev, thiab qhov hnyav nce. Tej zaum cov kev mob tshwm sim loj muaj xws li angioedema, kev siv tshuaj tsis raug, thiab muaj kev pheej hmoo tua tus kheej. Thaum pregabalin intermediates tau noj ntawm cov koob tshuaj ntau dhau lub sijhawm ntev, kev quav tshuaj yuav tshwm sim, tab sis yog tias noj ntawm cov koob tshuaj ib txwm muaj kev pheej hmoo ntawm kev quav tshuaj tsawg. Nws raug cais raws li GABA analogue.
Parke-Davis tau tsim pregabalin intermediates ua tus ua tiav rau gabapentin thiab tau coj mus rau kev lag luam los ntawm Pfizer tom qab lub tuam txhab tau txais Warner-Lambert. Yuav tsum tsis muaj generic version muaj nyob rau hauv lub tebchaws United States txog 2018. Ib tug generic version muaj nyob rau hauv Canada thiab lub tebchaws United Kingdom. Hauv Teb Chaws Asmeskas nws raug nqi txog 300-400 USD ib hlis. Pregabalin yog Schedule V tswj cov tshuaj nyob rau hauv Txoj Cai Tswj Cov Tshuaj ntawm 1970 (CSA).
