Pregabalin 99% CAS 148553-50-8
Chiyambi:
| Dzina la Chemical: | Pregabalin |
| Mawu ofanana ndi mawu: | 3-(Aminomethyl) -5-methyl-hexanoic acid |
| Cas No.: | 148553-50-8 |
| Molecular formula: | C8H17NO2 |
| Kulemera kwa Molecular: | 159.23 |
| Kapangidwe ka Molecular: |
-Main Quality index:
[Katundu]]: oyera ngati galasi lolimba.
[Zokhutira]]: ≥99.0%
[Kuzungulira kwachindunji]]: [α]D20+9.5~+11.5o(C=1,H2O)
-Gwiritsani ntchito:
Amagwiritsidwa ntchito ngati anticonvulsion, anti-epileptic mankhwala.
-Kufotokozera
Pregabalin, yogulitsidwa pansi pa dzina la Lyrica pakati pa ena, ndi mankhwala omwe amagwiritsidwa ntchito pochiza khunyu, ululu wa neuropathic, fibromyalgia, ndi matenda ovutika maganizo.Kugwiritsiridwa ntchito kwake kwa khunyu kumakhala ngati chithandizo chowonjezera cha khunyu pang'ono kapena popanda kuwonjezereka kwachiwiri kwa akuluakulu.Zina mwazomwe zimagwiritsidwa ntchito pa pregabalin intermediates zimaphatikizapo matenda osakhazikika a mwendo, kupewa mutu waching'alang'ala, kusokonezeka kwa chikhalidwe cha anthu, komanso kusiya mowa.Mukagwiritsidwa ntchito musanachite opaleshoni sizikuwoneka kuti zikukhudza ululu pambuyo pa opaleshoni koma zingachepetse kugwiritsa ntchito opioid.
Zotsatira zodziwika bwino ndi izi: kugona, kusokonezeka, vuto la kukumbukira, kusayenda bwino kwa magalimoto, pakamwa pouma, vuto la masomphenya, ndi kunenepa.Zotsatira zoyipa zomwe zingachitike ndi angioedema, kugwiritsa ntchito molakwika mankhwala osokoneza bongo, komanso chiwopsezo chodzipha.Pamene pregabalin intermediates imatengedwa pa mlingo waukulu kwa nthawi yaitali, kuledzera kumatha kuchitika, koma ngati kutengedwa pamlingo wanthawi zonse chiwopsezo cha kusuta chimakhala chochepa.Amagawidwa ngati analogue ya GABA.
Parke-Davis adapanga pregabalin intermediates ngati wolowa m'malo wa gabapentin ndipo adabweretsedwa pamsika ndi Pfizer kampaniyo itapeza Warner-Lambert.Sipayenera kukhala generic version ku United States mpaka 2018. Mtundu wa generic ukupezeka ku Canada ndi United Kingdom.Ku US zimawononga pafupifupi 300-400 USD pamwezi.Pregabalin ndi chinthu cholamulidwa ndi Schedule V pansi pa Controlled Substances Act ya 1970 (CSA).
