Pregabalin 99% CAS 148553-50-8
Iriburiro:
Izina ryimiti: | Pregabalin |
Synonyme: | 3- (Aminomethyl) -5-methyl-hexanoic aside |
Cas No.: | 148553-50-8 |
Inzira ya molekulari: | C8H17NO2 |
Uburemere bwa molekile: | 159.23 |
Imiterere ya molekulari: |
-Icyerekezo cyiza cyiza:
[Umutungo]]: cyera kristal-isa ikomeye.
[Ibirimo]]: ≥99.0%
[Kuzenguruka byihariye]]: [α] D20 + 9.5 ~ + 11.5o (C = 1, H.2O)
-Koresha:
Ikoreshwa nka anticonvulsion, imiti igabanya ubukana.
-Gusobanura
Pregabalin, igurishwa ku izina rya Lyrica mu zindi, ni imiti ikoreshwa mu kuvura igicuri, ububabare bwa neuropathique, fibromyalgia, n'indwara yo guhangayika muri rusange.Ikoreshwa ryigicuri ni nkiyongewe kumiti yo gufata igice hamwe cyangwa nta rusange rusange mubantu bakuru.Bimwe mubidakoreshwa muburyo bwo guhuza pregabalin harimo syndrome yamaguru ituje, kwirinda migraine, ihungabana ryimibereho, no kunywa inzoga.Iyo ikoreshejwe mbere yo kubagwa ntabwo bigaragara ko igira ingaruka kububabare nyuma yo kubagwa ariko irashobora kugabanya ikoreshwa rya opioide.
Ingaruka zisanzwe zirimo: gusinzira, urujijo, ibibazo byo kwibuka, guhuza moteri nabi, umunwa wumye, ikibazo cyo kureba, no kongera ibiro.Ingaruka zikomeye zishobora kuba zirimo angioedema, gukoresha ibiyobyabwenge, ndetse no kwiyongera kwiyahura.Iyo abahuza pregabalin bafashwe ku kigero kinini mugihe kirekire, ibiyobyabwenge birashobora kubaho, ariko iyo bifashwe mubisanzwe dosiye ibyago byo kwizizirwa ni bike.Byashyizwe mubikorwa nka GABA.
Parke-Davis yateje imbere abahuza pregabalin nk'umusimbura wa gabapentin hanyuma azanwa ku isoko na Pfizer nyuma yuko sosiyete iguze Warner-Lambert.Ntabwo hagomba kubaho verisiyo rusange iboneka muri Amerika kugeza muri 2018. Ubwoko rusange buraboneka muri Kanada no mubwongereza.Muri Amerika igura hafi 300-400 USD buri kwezi.Pregabalin ni gahunda ya V igenzurwa hakurikijwe amategeko agenga ibintu byo mu 1970 (CSA).