Protein ichangobva kuwanikwa inotsigira kunatswa kwakanaka kweRare Earth
Protein ichangobva kuwanikwa inotsigira kunatswa kwakanaka kweRare Earth Mune bepa richangoburwa rakaburitswa muJournal yeBiological Chemistry, vaongorori veETH Zurich vanotsanangura kuwanikwa kwelanpepsy, puroteni inosunga zvakanyanya lanthanides - kana zvisingawanzo zvinhu zvepasi - uye kuvasarura kubva kune mamwe mamineral nesimbi. Nekuda kwekufanana kwavo nemamwe maion esimbi, kucheneswa kweREE kubva kune zvakatipoteredza kunonetsa uye kune hupfumi chete munzvimbo shoma. Nekuziva izvi, masayendisiti akafunga kuongorora zvipenyu zvebhayoloji zvine hunyanzvi hwekusunga kwelanthanides senzira dzinogona kupa nzira yekumberi. Danho rekutanga raive rekuongorora zvidzidzo zvekare zvinoratidza kuti zvisikwa zvakashanduka zvakasiyana-siyana zvemapuroteni kana mamorekuru madiki kuti asvitse lanthanides. Mamwe mapoka ekutsvaga akawana kuti mamwe mabhakitiriya, methylotrophs anoshandura methane kana methanol, ane ma enzymes anoda lanthanides munzvimbo dzawo dzinoshanda. Kubva zvakawanikwa zvekutanga mundima iyi, kuzivikanwa uye hunhu hwemapuroteni anobatanidzwa mukunzwa, kutora, uye kushandiswa kwelanthanides, yave nzvimbo iri kubuda yekutsvaga. Kuti vaone vatambi vatsva mulanthanome, Jethro Hemmann naPhilipp Keller pamwe chete nevabatsiri kubva kuD-BIOL uye murabhoritari yaDetlef Günther kuD-CHAB, vakadzidza mhinduro yelanthanide yeobligate methylotroph Methylobacillus flagellatus. Nokuenzanisa proteome yemasero akakura muhupo uye kusavapo kwelanthanum, vakawana mapuroteni akati wandei asina kumboita hukama nekushandiswa kwelanthanide. Pakati pavo paiva nepuroteni duku yebasa risingazivikanwi, iro boka racho zvino rakatumidza kuti lanpepsy. In vitro characterization yeprotein yakaratidza kusunga nzvimbo dze lanthanides dzine high specificity ye lanthanum pamusoro pekemikari yakafanana necalcium. Lanpepsy inokwanisa kupfumisa lanthanides kubva kune mhinduro uye nekudaro inobata mukana wekuvandudza kwe bioinspired maitiro ekucheneswa kwakasimba kwepasi isingawanzo.
Nguva yekutumira: Mar-08-2023