Pregabalin 99% CAS 148553-50-8
Nhanganyaya:
| Chemical Name: | Pregabalin |
| Mashoko anoreva zvakafanana: | 3-(Aminomethyl) -5-methyl-hexanoic acid |
| Cas No.: | 148553-50-8 |
| Molecular Formula: | C8H17NO2 |
| Molecular Weight: | 159.23 |
| Molecular Structure: |
-Main Quality index:
[Chinhu]]: chena sekristaro-yakasimba.
[Zviri mukati]]: ≥99.0%
[Kutenderera chaiko]]: [α]D20+9.5~+11.5o(C=1,H2O)
-Kushandisa:
Inoshandiswa se anticonvulsion, anti-epileptic drug.
-Descript
Pregabalin, inotengeswa pasi pezita rezita rekuti Lyrica pakati pevamwe, mushonga unoshandiswa kurapa pfari, neuropathic kurwadziwa, fibromyalgia, uye generalized kusagadzikana kusagadzikana. Kushandiswa kwaro kwepfari kwakafanana nekuwedzera kurapa kwekubatwa nepfari uye kana pasina chechipiri generalization muvakuru. Zvimwe zve-off-label zvinoshandiswa zve pregabalin intermediates zvinosanganisira kusagadzikana kwegumbo syndrome, kudzivirira migraines, kushushikana kwemagariro evanhu, uye kunwa doro. Kana ikashandiswa kuvhiyiwa kusati kwaita senge inokanganisa marwadzo mushure mekuvhiyiwa asi inogona kuderedza kushandiswa kwemaopioid.
Migumisiro yakajairika inosanganisira: kurara, kuvhiringidzika, kunetseka nendangariro, kusafambisa zvakanaka mota, muromo wakaoma, dambudziko rekuona, uye kuwedzera uremu. Zvingangove zvakakomba mhedzisiro zvinosanganisira angioedema, kushandiswa zvisina kunaka kwezvinodhaka, uye njodzi yakawedzera yekuzviuraya. Kana pregabalin intermediates inotorwa pamadosi akakwira kwenguva yakareba, kupindwa muropa kunogona kuitika, asi kana ikatorwa pamazuva ese njodzi yekupindwa muropa yakaderera. Inotaridzwa seGABA analogue.
Parke-Davis akagadzira pregabalin intermediates seanotsiva gabapentin uye akaunzwa kumusika naPfizer mushure mekunge kambani yawana Warner-Lambert. Hapachave neshanduro yegeneric inowanikwa muUnited States kusvika 2018. Imwe generic version inowanikwa kuCanada nekuUnited Kingdom. MuUS inodhura nezve 300-400 USD pamwedzi. Pregabalin iSchedule V inodzorwa chinhu pasi peControlled Substances Act ye1970 (CSA).
