I-Calcium Hydroxyapatite HAP CAS 1306-06-5

Incazelo emfushane:

I-Calcium Hydroxyapatite/HAP
I-Hydroxyapatite, ebizwa nangokuthi i-hydroxylapatite (HA), iwuhlobo lwamaminerali oluvela ngokwemvelo lwe-calcium apatite enefomula ethi Ca5(PO4)3(OH), kodwa kuvame ukubhalwa Ca10(PO4)6(OH)2 ukukhombisa ukuthi iyunithi yekristalu. iseli lakhiwe izinhlangano ezimbili. I-Hydroxyapatite iyi-endmember ye-hydroxyl yeqembu le-apatite eliyinkimbinkimbi. I-hydroxyapatite powder ehlanzekile imhlophe. Ama-apatite enziwa ngokwemvelo angaba nombala onsundu, ophuzi, noma oluhlaza okotshani, uma kuqhathaniswa nokushintsha kombala kwe-fluorosis yamazinyo.
Kufika ku-50% ngevolumu kanye ne-70% ngesisindo sethambo lomuntu kuyindlela eguquliwe ye-hydroxyapatite, eyaziwa ngokuthi i-bone mineral.I-Carbonated calcium-deficient hydroxyapatite iyiminerali eyinhloko okwakhiwa ngayo koqweqwe lwamazinyo kanye ne-dentin. Amakristalu e-Hydroxyapatite ayatholakala futhi ekubalweni okuncane, ngaphakathi kwe-pineal gland nezinye izakhiwo, ezaziwa ngokuthi i-corpora arenacea noma 'isihlabathi sobuchopho'.

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

I-Calcium Hydroxyapatite/HAP

I-Hydroxyapatite, futhi ebizwai-hydroxylapatite(HA), iwuhlobo lweminerali eyenzeka ngokwemvelo ye-calcium apatite enefomula ethi Ca5(PO4)3(OH), kodwa ngokuvamile ibhalwa ngokuthi Ca10(PO4)6(OH)2 ukuze ibonise ukuthi i-crystal unit cell iqukethe izinhlangano ezimbili. I-Hydroxyapatite iyi-endmember ye-hydroxyl yeqembu le-apatite eliyinkimbinkimbi. Okumsulwai-hydroxyapatite powderkumhlophe. Ama-apatite enziwa ngokwemvelo angaba nombala onsundu, ophuzi, noma oluhlaza okotshani, uma kuqhathaniswa nokushintsha kombala kwe-fluorosis yamazinyo.
Kufika ku-50% ngevolumu kanye ne-70% ngesisindo sethambo lomuntu kuyindlela eguquliwe ye-hydroxyapatite, eyaziwa ngokuthi i-bone mineral.I-Carbonated calcium-deficient hydroxyapatite iyiminerali eyinhloko okwakhiwa ngayo koqweqwe lwamazinyo kanye ne-dentin. Amakristalu e-Hydroxyapatite ayatholakala futhi ekubalweni okuncane, ngaphakathi kwe-pineal gland nezinye izakhiwo, ezaziwa ngokuthi i-corpora arenacea noma 'isihlabathi sobuchopho'.

Isicelo

1. I-Hydroxyapatite ikhona emathanjeni namazinyo; ithambo lenziwa ngokuyinhloko ngamakristalu e-HA afakwe ku-collagen matrix -- 65 kuya ku-70% wesisindo samathambo yi-HA. Ngokufanayo, i-HA ingamaphesenti angama-70 kuye kwangama-80 wesisindo se-dentin kanye noqweqwe lwamazinyo emazinyweni. Koqweqwe lwawo, i-matrix ye-HA yakhiwa ama-amelogenins nama-enamelins esikhundleni se-collagen.
I-Hydroxylapatite deposits kuma-tendon azungeze amalunga iphumela esimweni sezokwelapha i-calcific tendinitis.

2. I-HA iya ngokuya isetshenziselwa ukwenzaizinto zokuhlanganisa amathambokanye ne-prosthetics yamazinyo nokulungiswa. Amanye ama-implants, isb ukushintshwa kwenyonga, izifakelo zamazinyo kanye nezixhumi ze-conduction yamathambo, zimbozwe nge-HA. Njengoba izinga lokuqedwa lendabuko le-hydroxyapatite in-vivo, cishe i-10 wt% ngonyaka, liphansi kakhulu kunezinga lokukhula kwezicubu zamathambo ezisanda kwakhiwa, ekusetshenzisweni kwayo njengezinto ezithatha indawo yamathambo, kufunwa izindlela zokuthuthukisa izinga lokuncibilika kwayo futhi ngaleyo ndlela kukhuthaze ukusebenza okungcono kwe-bioactivity.

3. I-Microcrystalline hydroxyapatite (MH) imakethwa njengesengezo "sokwakha amathambo" ngokumuncwa okuphakeme uma kuqhathaniswa ne-calcium.

Ukucaciswa

Singahlinzeka nge-Hydroxyapatite kokubili ifomu le-powder kanye nefomu le-granule.

I-Modle	Isimo	Usayizi wezinhlayiya	Ubumsulwa	Isicelo
HAP01	Inaliti	60nm	96%	Inhlabathi yokuxubha, inhlabathi
HAP02	Inaliti	40nm	96%	Ukuhlukaniswa kanye ne-chromatography yamaprotheni
HAP03	Inaliti	20nm	97.5%	Ukuhlanzeka okuphansi kwethambo lokwenziwa
HAP04	Inaliti	20*150nm	99%	Ukuhlanzeka okuphezulu kwethambo lokwenziwa
HAP05	Induku emfushane	30*100nm	99%	Ithambo lokwenziwa, ilunga lokwenziwa
HAP06	I-Spherical	12 um	99%	Ukufakwa kwamathambo okwenziwa
HAP07	I-Spherical	12 um	96%	Inhlabathi yokuxubha, inhlabathi
HAP08	I-Spherical	29 um	96%	I-Ceramic enamathela