Pregabalin 99% Cas 148553-50-8
Isingeniso:
| Igama lamakhemikhali: | Pregabalin |
| Izimpawu: | 3- (Aminomethyl) -5-methy-hexanoic acid |
| Cas Cha: | 148553-50-8 |
| Ifomula ye-Molecular: | C8H17NO2 |
| Isisindo samangqamuzana: | 159.23 |
| Isakhiwo samangqamuzana: |
-I-Main Quality Index:
[Impahla]]: I-Crystal Emhlophe-Like Swolid.
[Okuqukethwe]]: ≥99.0%
[Ukujikeleza okuthile]]: [α] D20 + 9.5 ~ + 11.5o (c = 1, h2O)
-Sebenzisa:
Isetshenziswa njenge-anticonviesion, isidakamizwa esi-anti-sesithuthwayo.
-BATI
I-Pregabalin, ithengiswa ngaphansi kwegama lomkhiqizo uLyrica phakathi kwabanye, umuthi osetshenziselwa ukwelapha isithuthwane, izinhlungu ze-neuropathic, i-fibromyalgia, kanye nokuphazamiseka kokukhathazeka okujwayelekile. Ukusetshenziswa kwayo kwesithuthwane kunjengokwelashwa kwesengezo kokuhlaselwa okuyingxenye noma ngaphandle kwako lesibili okwenziwe ngabantu abadala. Ukusetshenziswa kokukhishwa kwemali okungekho emthethweni kwe-Pregabalin Intermediates kufaka phakathi i-Restless Leg Syndrome, ukuvikela ama-migraines, ukuphazamiseka kokukhathazeka kwezenhlalo, nokuhoxiswa kotshwala. Lapho isetshenziswa ngaphambi kokuhlinzwa akubonakali kuthinta izinhlungu ngemuva kokuhlinzwa kepha kunganciphisa ukusetshenziswa kwama-opioids.
Imiphumela emibi ejwayelekile ifaka: Ukulala, ukudideka, inkathazo ngememori, ukuxhumanisa kwezimoto ezingezinhle, umlomo owomile, inkinga ngombono, nokuzuza kwesisindo. Imiphumela emibi engathi sína ifaka phakathi i-angioedema, ukusetshenziswa kabi kwezidakamizwa, kanye nengozi eyandayo yokuzibulala. Lapho i-pregabalin ephakathi ithathwa ngemithamo ephezulu isikhathi eside, kungenzeka umlutha, kepha uma kuthathwe ngokujwayelekile imithamo yengozi yokulungiswa iphansi. Kuhlukaniswa njenge-gaba analogue.
I-Parke-Davis yathuthukisa i-Pregabalin i-Intermediates njenge-Enalondali eGabapentin futhi yalethwa emakethe ngePfizer ngemuva kokuthi inkampani ithole iWarner-Lambert. Akunakuba khona inguqulo ejwayelekile etholakala e-United States kuze kube ngu-2018. Uhlobo olujwayelekile luyatholakala eCanada nase-United Kingdom. E-US kubiza cishe ama-300-400 USD ngenyanga. I-Pregabalin iyinhlelo v elawulwa yinto ngaphansi koMthetho Wezinto Ezilawulwa ngo-1970 (CSA).
