Cov protein uas tau tshawb pom tshiab txhawb nqa kev ua kom zoo ntawm Rare ntiaj teb
Cov protein uas tau tshawb pom tshiab txhawb nqa kev ua kom zoo ntawm Rare ntiaj teb Nyob rau hauv ib daim ntawv tsis ntev los no luam tawm nyob rau hauv Phau ntawv Journal of Biological Chemistry, cov kws tshawb fawb ntawm ETH Zurich piav qhia txog kev tshawb pom ntawm lanpepsy, ib qho protein uas tshwj xeeb khi lanthanides - lossis cov ntsiab lus tsis tshua muaj hauv ntiaj teb - thiab cais lawv los ntawm lwm yam minerals thiab hlau. Vim tias lawv zoo sib xws rau lwm cov hlau ions, kev ua kom huv ntawm REE los ntawm ib puag ncig yog cumbersome thiab kev lag luam tsuas yog nyob rau hauv ob peb qhov chaw. Paub txog qhov no, cov kws tshawb fawb tau txiav txim siab los tshawb nrhiav cov khoom siv roj ntsha uas muaj kev sib txuam siab rau lanthanides ua cov txheej txheem uas tuaj yeem muab txoj hauv kev rau pem hauv ntej. Thawj kauj ruam yog los tshuaj xyuas cov kev tshawb fawb yav dhau los uas qhia tias qhov xwm txheej tau hloov pauv ntau yam ntawm cov proteins lossis cov molecules me me kom tshem tawm lanthanides. Lwm pawg tshawb fawb tau tshawb pom tias qee cov kab mob, methylotrophs uas hloov methane lossis methanol, muaj cov enzymes uas xav tau lanthanides hauv lawv qhov chaw nquag. Txij li thaum thawj qhov kev tshawb pom nyob rau hauv daim teb no, kev txheeb xyuas thiab cov yam ntxwv ntawm cov proteins koom nrog hauv kev nkag siab, kev siv, thiab kev siv lanthanides, tau dhau los ua qhov kev tshawb fawb tshiab. Txhawm rau txheeb xyuas cov neeg ua yeeb yam tshiab hauv lanthanome, Jethro Hemmann thiab Philipp Keller ua ke nrog cov neeg koom tes los ntawm D-BIOL thiab lub chaw soj nstuam ntawm Detlef Günther ntawm D-CHAB, tau kawm txog cov lus teb lanthanide ntawm obligate methylotroph Methylobacillus flagellatus. Los ntawm kev sib piv cov proteome ntawm cov hlwb loj hlob nyob rau hauv lub xub ntiag thiab tsis muaj lanthanum, lawv pom ob peb cov proteins uas yav tas los tsis hais txog kev siv lanthanide. Ntawm lawv yog cov protein me me uas tsis paub ua haujlwm, uas tam sim no pab pawg hu ua lanpepsy. Nyob rau hauv vitro tus yam ntxwv ntawm cov protein qhia kev khi qhov chaw rau lanthanides nrog siab tshwj xeeb rau lanthanum tshaj cov tshuaj calcium uas zoo sib xws. Lanpepsy muaj peev xwm ntxiv lanthanides los ntawm kev daws teeb meem thiab yog li tuav lub peev xwm rau kev txhim kho cov txheej txheem bioinspired rau kev ua kom huv huv ntawm cov av tsawg.
Post lub sij hawm: Mar-08-2023