Pregabalin 99% CAS 148553-50-8
Okwu mmalite:
| Aha kemịkalụ: | Pregabalin |
| Ụdị okwu: | 3- (Aminomethyl) -5-methyl-hexanoic acid |
| Nọmba Cas: | 148553-50-8 |
| Ụdị molekụla: | C8H17NO2 |
| Arọ Molecular: | 159.23 |
| Ọdịdị Molecular: |
-Ndekọ ogo isi:
[Ngwongwo]]: kristal ọcha dị ka ihe siri ike.
[Ọdịnaya]]: ≥99.0%
[Ntụgharị pụrụ iche]: [α]D20+9.5~+11.5o(C=1,H2O)
-Jiri:
A na-eji ya dị ka anticonvulsion, ọgwụ mgbochi epileptic.
-Nkọwa
Pregabalin, nke a na-ere n'okpuru aha aha Lyrica n'etiti ndị ọzọ, bụ ọgwụ a na-eji agwọ ọrịa Akwụkwụ na-adọ, nhụjuanya neuropathic, fibromyalgia, na nsogbu nchekasị zuru oke. Ojiji ya maka Akwụkwụ na-adọ bụ ihe mgbakwunye mgbakwunye maka ọdịdọ akụkụ nke nwere ma ọ bụ na-enweghị mkpokọta nke abụọ na ndị okenye. Ụfọdụ n'iji akara pregabalin intermediates gụnyere ọrịa ụkwụ na-adịghị agwụ agwụ, mgbochi nke migraines, nsogbu nchekasị ọha na eze, na ịṅụ mmanya na-aba n'anya. Mgbe ejiri ya tupu ịwa ahụ ọ naghị emetụta mgbu mgbe ịwachara ahụ mana ọ nwere ike ibelata ojiji nke opioids.
Mmetụta ndị a na-ahụkarị gụnyere: ihi ụra, mgbagwoju anya, nsogbu na ebe nchekwa, nhazi moto na-adịghị mma, ọnụ nkụ, nsogbu na ọhụụ, na ibu ibu. Mmetụta ndị nwere ike ịdị njọ gụnyere angioedema, iji ọgwụ eme ihe n'ụzọ na-ezighị ezi, na ihe ize ndụ igbu onwe onye na-abawanye. Mgbe a na-ewere pregabalin intermediates na nnukwu doses ogologo oge, ihe riri ahụ nwere ike ime, mana ọ bụrụ na ewere ya na usoro mbụ, ihe ize ndụ nke riri ahụ dị ala. A na-ekewa ya dị ka analogue GABA.
Parke-Davis mepụtara pregabalin intermediates dị ka onye ga-anọchi gabapentin ma Pfizer wetara ya n'ahịa mgbe ụlọ ọrụ ahụ nwetasịrị Warner-Lambert. A gaghị enwe ụdị ọnyà ọnyà dị na United States ruo n'afọ 2018. Ụdị ọnyà dị na Canada na United Kingdom. Na US ọ na-efu ihe dịka 300-400 USD kwa ọnwa. Pregabalin bụ ihe a na-achịkwa nhazi oge V n'okpuru Iwu Ihe Ejikwa nke 1970 (CSA).
