Pregabalin 99% CAS 148553-50-8

Inkcazelo emfutshane:

Igama lemveliso: Pregabalin
Cas: 148553-50-8
Imbonakalo:emhlophe njengekristale eqinileyo
Ubunyulu:99%min
Iphakheji: 1kg / ibhegi, 25kg / igubu
Isicelo:Isetyenziswa njenge-anticonvulsion, ichiza elichasayo lokuxhuzula.


Iinkcukacha zeMveliso

Iithegi zeMveliso

Pregabalin 99% CAS148553-50-8

Intshayelelo:

Igama leMchiza: Pregabalin
Izithethantonye: 3-(Aminomethyl) -5-methyl-hexanoic acid
Inombolo yeCas: 148553-50-8
Ifomula yemolekyuli: C8H17NO2
Ubunzima beMolekyuli: 159.23
Ulwakhiwo lweMolekyuli:

-Isalathisi soMgangatho oPhambili:

[Ipropathi]]: okuqinileyo okumhlophe okwekristale.
[Umxholo]]: ≥99.0%
[Ujikelezo olukhethekileyo]]: [α]D20+9.5~+11.5o(C=1,H2O)

 -Sebenzisa:

Isetyenziswa njenge-anticonvulsion, i-anti-epileptic drug.

-Inkcazo

I-Pregabalin, ethengiswe phantsi kwegama le-brand ye-Lyrica phakathi kwabanye, liyeza elisetyenziselwa ukunyanga ukuxhuzula, iintlungu ze-neuropathic, i-fibromyalgia, kunye nokuphazamiseka kwengqondo ngokubanzi.Ukusetyenziswa kwayo kwisifo sokuxhuzula njengonyango olongezelelekileyo lokuxhuzula ngokuyinxenye kunye okanye ngaphandle kokwenziwa ngokubanzi okwesibini kubantu abadala.Olunye usetyenziso olungekho ngeleyibhile lwe-pregabalin intermediates lubandakanya i-restless leg syndrome, uthintelo lwe-migraines, ukuphazamiseka kwentlalo, kunye nokuyeka utywala.Xa isetyenziswe phambi kotyando ayibonakali ichaphazela intlungu emva kotyando kodwa inokunciphisa ukusetyenziswa kwe-opioids.

Iziphumo eziqhelekileyo ezichaphazelekayo ziquka: ukulala, ukudideka, inkathazo ngememori, ukulungelelaniswa kwemoto, umlomo owomileyo, ingxaki yombono, kunye nokuzuza ubunzima.Iziphumo ebezingalindelekanga ezimandundu ziquka i-angioedema, ukusetyenziswa kakubi kweziyobisi, kunye nokwanda komngcipheko wokuzibulala.Xa i-pregabalin intermediates ithathwa kwiidosi eziphezulu kwixesha elide, umlutha unokwenzeka, kodwa ukuba kuthathwe kwiidosi eziqhelekileyo umngcipheko wokuba likhoboka uphantsi.Ihlelwa njenge-analogue ye-GABA.

UParke-Davis uphuhlise i-pregabalin intermediates njengendlalifa ye-gabapentin kwaye yaziswa kwintengiso nguPfizer emva kokuba inkampani ifumene iWarner-Lambert.Akufuneki kubekho inguqulelo yegeneric ekhoyo eUnited States de kube ngu-2018. Inguqulelo yegeneric iyafumaneka eKhanada naseUnited Kingdom.E-US ixabisa malunga ne-300-400 USD ngenyanga.I-Pregabalin yinto elawulwayo yeShedyuli V phantsi koMthetho wezinto eziLawulwayo we-1970 (CSA).

 


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